Allopurinol ya agalu: mlingo ndi zotsatirapo zake

Mlembi: John Stephens
Tsiku La Chilengedwe: 24 Jayuwale 2021
Sinthani Tsiku: 20 Novembala 2024
Anonim
Allopurinol ya agalu: mlingo ndi zotsatirapo zake - Ziweto
Allopurinol ya agalu: mlingo ndi zotsatirapo zake - Ziweto

Zamkati

Allopurinol ndi mankhwala omwe amagwiritsidwa ntchito ngati mankhwala a anthu kuti achepetse uric acid mu plasma ndi mkodzo, chifukwa imalepheretsa enzyme inayake yomwe imapangika. Pazowona zanyama, makamaka agalu, ndi mankhwala omwe amagwiritsidwa ntchito kuphatikiza ma antimonials kapena miltefosine pochiza leishmaniasis.

Ngati mukufuna kudziwa zambiri za mankhwalawa, pitirizani kuwerenga nkhaniyi ndi PeritoAnimal, momwe timakambirana za galu allopurinol, momwe amagwiritsidwira ntchito, Mlingo woyenera komanso zotsatirapo zoyipa zomwe zingachitike.

Kodi allopurinol ya agalu ndi yotani?

Allopurinol ndi choletsa mavitamini zomwe, makamaka, zimalepheretsa enzyme yomwe imathandizira kusintha kwa xanthine kukhala uric acid. Sigwiritsidwe ntchito yokha, koma imagwira ntchito ngati mankhwala owonjezera a leishmanicidal, antimony kapena miltefosine, kuyesa kuthetseratu tizilomboto m'matumba onse. Mwanjira imeneyi, kugwiritsa ntchito allopurinol mu agalu kumachepetsedwa kukhala chimodzi: chithandizo chotsutsana ndi leishmania.


Mpaka liti kupereka allopurinol kwa galu?

Mankhwalawa amaperekedwa pakamwa ndi chithandizo chake amatha miyezi isanu ndi umodzi mpaka chaka. Palinso milandu pomwe chithandizo chotalika chimakhazikitsidwa. Komabe, kuwunikiranso ndikuwatsata pamlanduwo ndikofunikira pambuyo pokhazikitsa chithandizo, poganizira kuti mafupipafupi awunikiridwa ndi veterinarian, popeza malinga ndi kuopsa kwa mulandu uliwonse kuyenera kukhala payokha.

Chithandizo cha Allopurinol chikuyenera kutsata wodwala. Chitsanzo chothandiza chingakhale miltefosine tsiku lililonse pafupifupi mwezi umodzi, kuphatikiza ndi allopurinol tsiku lililonse pafupifupi miyezi 8.

Allopurinol agalu omwe ali ndi leishmania

Monga tanenera m'gawo lapitalo, allopurinol imagwiritsidwa ntchito pochiza leishmania. Leishmaniasis ndi a matenda a parasitic chifukwa cha protozoan wofalitsidwa ndi kuluma kwa vekitala: udzudzu wouluka mumchenga. Ndi zoonosis yogawidwa padziko lonse lapansi komanso yofunika kwambiri, chifukwa chake, kuwonjezera pa njira zopewera zochepetsera kufalikira kwake (katemera, makola otetezera ndi mapaipi, otetezera chitetezo), agalu onse omwe ali ndi matendawa ayenera kuthandizidwa.


Agalu odwala ndi omwe ali ndi zizindikilo zamankhwala ndipo matenda a leishmania amatsimikiziridwa ndi matenda a labotale. Ndi matenda osadziwika, ndiye kuti, Zitha kuchitika ndi zizindikilo zingapo zamankhwala, kotero ndikofunikira kukhala ndi mbiri yabwino ya miliri ya malo komwe galu amakhala komanso chitetezo chake. Zina mwazizindikirozi ndi: zotupa zotupa, zopunduka, zotulutsa magazi m'mphuno, zammphuno ndi phazi pedi hyperkeratosis, ulesi, ndi zina zambiri. Matendawa amatha kutchulidwa ngati visceral kapena cutaneous leishmaniasis.

Ndizodziwika kuti, kuwonjezera pa leishmania, galu amadwala matenda ena opatsirana m'magazi chifukwa amalumikizana kwambiri ndi galu wazodzitchinjiriza. Chifukwa chake, tiyenera kuyamba kuchiritsa leishmaniasis tikakhala ndi galu wokhazikika, ndiye kuti, ngati matenda ayambitsa kuchepa kwa magazi, kuperewera kwa impso, dermatitis, ndi zina zambiri, tiyenera kuchiza izi.


Miltefosine ndi ma antimonials ndi mankhwala a leishmanicidal (omwe amachotsa tiziromboti) ndipo zochita zawo zimathamanga komanso mwamphamvu kwambiri, pomwe allopurinol ndi leishmaniostatic (imaletsa kuchulukana kwa tiziromboti). Pachifukwa ichi, ndizofala kugwiritsa ntchito mankhwalawa. Komabe, azachipatala ambiri amakonda yang'anani njira zina kuposa allopurinol chifukwa cha zovuta zoyipa zomwe mankhwalawa ali nazo kwa odwala.

Mlingo wa Allopurinol wa agalu

Mlingo wa allopurinol wa agalu okhazikitsidwa kuti azithandizira leishmaniasis ndi 10 mg pa kg ya kulemera maola 12 aliwonse, mwachitsanzo kawiri pa tsiku.

Mawonekedwe omwe alipo a mankhwala ndi mapiritsi a 100 mg ndi 300 mg a allopurinol. Chifukwa chake, veterinarian angakuuzeni mapiritsi angati omwe muyenera kupereka malinga ndi kulemera kwa galu wanu. Komanso, kumbukirani kuti katswiriyu amadziwika kuti ndi nthawi yayitali bwanji yamankhwala, yomwe sayenera kuyimitsidwa popanda kuvomerezedwa kale.

Zotsatira zoyipa zonse za agalu

Pali zovuta ziwiri zoyipa zomwe allopurinol imatha kuyambitsa agalu akamalandira chithandizo:

  • xanthinuria: pamene purines imanyozetsedwa ndi ma enzyme ofanana, xanthine imapangidwa, ndipo izi, zimasandulika uric acid. Allopurinol imasokoneza kusintha kwa xanthine kukhala uric acid, yomwe imayenera kuthetsedwa mumkodzo, ndikupanga xanthine owonjezera ndipo zotsatira zake zimadzikundikira.
  • Urolithiasis: kuchuluka kwa makina a xanthine kumatha kupanga matumba okhala ndi zinthu zopangidwa ndikupanga ma urolith (miyala). Ma urolith awa ndiosalala, ndiye kuti, samawoneka ndi x-ray yosavuta, ndipo x-ray kapena kusiyanitsa ultrasound kumafunika kuti muwazindikire.

Zizindikiro zamatenda omwe amatha kuwona ndi matendawa ndi awa:

  • dysuria (kupweteka pokodza);
  • hematuria (magazi mumkodzo);
  • kusadziletsa kwamikodzo;
  • kutsekeka kwamikodzo;
  • kupweteka m'mimba.

Mutha kupeza zakudya zamagalu zopangidwa makamaka kuti zithandizire leishmaniasis. Amadziwika ndi zotsika za purine, zomwe zimalepheretsa mapangidwe a makina a xanthine. Kuphatikiza apo, ali ndi zinthu zomwe zimathandiza kuteteza mafupa, khungu komanso chitetezo chamthupi.

Njira Zina za Allopurinol za Agalu

Monga tidanenera m'zigawo zam'mbuyomu, zovuta za allopurinol zapangitsa kuti akatswiri azachipatala ambiri asankhe njira zina za mankhwalawa. Mwanjira imeneyi, kafukufuku waposachedwa[1] ikutsimikizira kuti osatulutsidwa, nucleotide-based nutraceutical imagwira ntchito polimbana ndi kukula kwa leishmania ndipo siyimabweretsa zosafunika.

Njira yatsopano yothandizira leishmania imatipangitsa kugwiritsa ntchito mankhwala atsopanowa omwe alibe zovuta. Choyipa chake ndikuti mankhwalawa ali ndi mtengo wokwera poyerekeza ndi allopurinol.

Nkhaniyi ndi yongofuna kudziwa zambiri, ku PeritoAnimal.com.br sitingathe kupereka chithandizo chamankhwala kapena mtundu uliwonse wa matenda. Tikukulangizani kuti mupite ndi chiweto chanu kuchipatala ngati chili ndi vuto lililonse.

Ngati mukufuna kuwerenga zina zambiri zofanana ndi Allopurinol ya agalu: mlingo ndi zotsatirapo zake, tikukulimbikitsani kuti mulowe mu gawo lathu la Mankhwala.