Cryptococcosis mu Amphaka - Zizindikiro ndi Chithandizo

Mlembi: Laura McKinney
Tsiku La Chilengedwe: 3 Epulo 2021
Sinthani Tsiku: 17 Novembala 2024
Anonim
Cryptococcosis mu Amphaka - Zizindikiro ndi Chithandizo - Ziweto
Cryptococcosis mu Amphaka - Zizindikiro ndi Chithandizo - Ziweto

Zamkati

Feline cryptococcosis ndiye Matenda omwe amayamba chifukwa cha bowa ofala kwambiri mu amphaka, komabe, kuchuluka kwake kwa ziweto ndizochepa. Cryptococcosis imachitika kawirikawiri m'mphuno, ndikuwonetsa edema yomwe nthawi zina imatha kudziwika bwino chifukwa cha kukula kwa fungal granuloma. Nthawi zina, cryptococcosis imakhudza mapapu, maso, dongosolo lamanjenje kapena imakhala ndi mawonekedwe, ikamachitika m'malo osiyanasiyana amthupi ikagawidwa kudzera munjira ya hematogenous kapena lymphatic. Chithandizochi chimagwiritsidwa ntchito pogwiritsa ntchito mankhwala omwe amapangidwira kupha yisiti ndipo, nthawi zina, kubwezeretsanso fungal granuloma mu mphaka kumathandizidwanso.


Munkhani iyi ya PeritoZinyama, tikambirana cryptococcosis mu amphaka, zizindikiro zake ndi chithandizo, kuti mumvetse bwino matenda ofalawa ndikuphunzira kuwazindikira.

feline cryptococcosis ndi chiyani?

Feline cryptococcosis ndi matenda opatsirana omwe amakhudza amphaka ndipo amayamba chifukwa cha bowa. Makamaka, wothandizirana ndi fungus yemwe amakhala nthawi zambiri amakhala Cryptococcus neoformans, kukhala matenda okhudzana ndi malo omwe kuli mbalame, makamaka nkhunda, chifukwa zimapezeka mu ndowe zawo. Ikhozanso kuyambitsidwa ndi Kryptococcus gattii, makamaka m'malo otentha kapena otentha, ndipo komwe kumayambitsa matenda ndikubzala mitengo ina.

Ndi yisiti yaying'ono kwambiri yogawa padziko lonse lapansi. Ili ndi kapisozi komwe, kuphatikiza pakuteteza kuuma, kumapangitsa kuti chitetezo chamthupi cha mphaka chizizindikire kuti chiziyambitsa chitetezo chamthupi chofunikira kuti chithetsedwe. Komabe, ndi matenda ochepa.


Chowopsa pakukula kwa cryptococcosis mu amphaka oyambitsidwa ndi C. Neoformans ndikupezeka kwa matenda opatsirana pogonana monga feline leukemia kapena feline immunodeficiency. Komabe, matendawa ndi C. gattii Zitha kuchitika mwa anthu omwe alibe chitetezo chamthupi. Komabe, mwa anthu omwe alibe chitetezo chokwanira matendawa amakhala owopsa kwambiri, pomwe mwa anthu omwe ali ndi chitetezo champhamvu chamthupi, matendawa amapezeka m'derali. mphuno, osafalikira.

Kodi pathogenesis ya cryptococcosis ndi yotani?

Chitsime chachikulu cha matenda a cryptococcosis amphaka ndi kudzera kupuma kwa yisiti, zomwe zimayikidwa kumtunda kwa mpweya, komwe zimapanga ma granulomas amphuno. Ngati afika kutsika kwa m'mapapo mwa mpweya, amayambitsa ma granulomas m'mapapu.


O bowa amatha kufalikira kumadera ena, monga mitsempha yapakatikati, kudzera m'magazi, ma lymphatic kapena kuwukira kwanuko kudzera pa cribriform wosanjikiza wa fupa la ethmoid, lomwe limalumikiza ubongo ndi mphako. Amathanso kufikira madera ena monga maso, nkhope ndi khungu. Ngati matendawa amapezeka kwambiri, yisiti imatha kufalikira ku ziwalo monga ndulu, mtima, impso, ziwalo zogaya, minofu, kapena ma lymph node.

Zizindikiro za cryptococcosis mu amphaka

Cryptococcosis itha kuyambitsa Zizindikiro zosiyana kwambiri zamatenda kutengera komwe yisiti imapezeka ndi momwe amafalitsira. Pakhoza kukhala mitundu ingapo ya cryptococcosis mu amphaka: m'mphuno, m'mapapo mwanga, mwamanjenje, ocular ndi systemic.

m'mphuno cryptococcosis

M'mphuno cryptococcosis mu amphaka, zizindikiro zofala kwambiri ndizopuma, ndi chapamwamba zizindikiro za thirakiti:

  • Mphuno yam'magazi kapena yamagazi kapena kutuluka kwamayiko awiri.
  • Rhinitis.
  • Kutupa m'mphuno.
  • Granulomas.
  • Kuswetsa.
  • Mitsinje ya kupuma.
  • Ache.
  • Kupuma kovuta.

Cryptococcosis m'mapapo mwanga

Mtundu wa cryptococcosis wamphaka umachitika yisiti imakhudza mapapo ndi ma granulomas, chibayo, komanso kulowa mkati mwa bronchi. kuchepetsa zizindikiro za kuthawa, monga:

  • Tsokomola.
  • Kupuma kovuta.
  • Malungo.
  • Phokoso m'mapapo mwanga.

Minyewa ya cryptococcosis

Cryptococcosis itha kukhudzanso dongosolo lamanjenje, pomwe limatha kuwonedwa. zizindikirowamanjenje zomwe zitha kukhala zotsatira za encephalitis kapena meningitis chifukwa chakupezeka kwa yisiti mumanjenje apakati, monga:

  • Kuchuluka kwa ophunzira (mydriasis).
  • Kusintha kwa zida.
  • Kusagwirizana.
  • Kusasamala.
  • Khungu lonse kapena pang'ono.

mawonekedwe a cryptococcosis

Yisiti ikalowa m'diso, zizindikiro izi zimachitika:

  • Chamawonedwe neuritis.
  • Chorioretinitis.
  • Mydriasis.

zokhudza zonse cryptococcosis

Cryptococcosis ikakhudza madera osiyanasiyana amphaka, a Zizindikiro zosiyanasiyana zitha kuchitika, uwu ndiye mtundu wovuta kwambiri wa matendawa. Zina mwazizindikirozi, izi ndi izi:

  • Malungo.
  • Tsokomola.
  • Kutsetsereka kwa pulmonary.
  • Matenda a anorexia.
  • Kuchepetsa thupi.
  • Kufooka.
  • Ataxia.
  • Zilonda za mucosal.
  • Kuvuta kuyenda.
  • Kusanza.
  • Kutsekula m'mimba.
  • Ma granulomas odulidwa.
  • Mafupa okulirapo.

Kuzindikira kwa cryptococcosis mu amphaka

Matendawa amathandizidwa, kuphatikiza pazizindikiro zamankhwala ndi mbiri yanyama ya nyama, zasayansi ndi mayeso owonjezera, kuphatikizapo kudzipatula ndi kudziwika kwa tizilombo toyambitsa matenda ndi cytology ndi chikhalidwe, komanso kutsimikiza kwa yisiti capsule antigen. Mayeso awa ndi awa:

  • THE cytology imagwiritsidwa ntchito pobowola malo omwe akhudzidwa, monga ma lymph node, masisa m'mphuno kapena pakhungu. Pambuyo pake, imawonedwa pansi pa microscope yokhala ndi utoto, monga Gram, methylene buluu, inki ya Wright ndi China, kuti iwonetse thupi. Ndi cholengedwa chosavuta kuzindikira chifukwa cha kapisozi kake ka polysaccharide.
  • THE chikhalidwe imagwiritsidwa ntchito kuchokera ku zitsanzo zamagetsi zamadzimadzi kapena ma exudates. Zitsanzo ziyenera kuphatikizidwa pa Sabouraud agar kapena magazi agar pakatentha pakati pa 25 ndi 35 ºC. Pambuyo maola 36-72, ngati zabwino, zowoneka zoyera zidzawoneka. madera a C. Neoformans ndi ocheperako kuposa a C. gattii. Kuti muzindikire yisiti, ndikofunikira kuwona kapisoziyo ndikutsimikizira mawonekedwe ake, monga kuthekera kwake kuchepetsa nitrate kukhala nitrites ndi hydrolyze urea.
  • Kuti mupeze capsule antigen, kuyesa kwa latex agglutination, kapena ELISA, Amagwiritsidwa ntchito ndi zitsanzo za seramu yamagazi, cerebrospinal fluid kapena mkodzo. Chiyesochi chimakhala chokhudzidwa kwambiri komanso chapadera mumphaka.

Zithunzi zojambula pachifuwa zitha kukhala zothandiza kuwonera kusintha kwamapapo ndi kwamapapo pakachitika pulmonary cryptococcosis.

Chithandizo cha feline cryptococcosis

Njira yothandizira ya cryptococcosis mu amphaka imaphatikizapo chithandizo ndi antifungal kupha yisiti ndi resection ya ma granulomas. THE opaleshoni resection imagwiridwa ndi amphaka okhala ndi ma granulomas m'mphuno monga cholumikizira kuchipatala ndi oletsa antifungal.

Mankhwala omwe amagwiritsidwa ntchito kwambiri pochizira cryptococcosis mu amphaka ndi awa:

  • Fluconazole: ndi mankhwala omwe amapezeka kwambiri masiku ano chifukwa ndiwothandiza komanso otetezeka kwambiri. Mlingo wa 50 mg / maola 12 amagwiritsidwa ntchito pakamwa. Imathandizanso pochiza matenda amitsempha podutsa chotchinga cha magazi ndi ubongo.
  • alireza: itraconazole ya amphaka imagwiranso ntchito ngati fluconazole, koma itha kukhala poizoni pachiwindi ndipo, chifukwa chake, imafunikira chidwi mwa mankhwala ake.
  • Ketoconazole: Ndiwothandiza koma siwothandiza pa cryptococcosis nervosa, ndipo imatha kuyambitsa zovuta zina monga kusanza ndi kusowa kwa njala amphaka.
  • Amphotericin B yokhala ndi 5-fluorocytosine: ndi mankhwala othandiza kwambiri pakakhala zizindikiro zamanjenje. Ankagwiritsidwa ntchito zaka zingapo zapitazo.

Mulimonsemo, ndikofunikira kupita kuchipatala cha owona za ziweto kuti katswiri akatsimikizire matendawo ndikupeza chithandizo chabwino kwambiri. Simuyenera kumwa katsi nokha.

Tsopano popeza mukudziwa zonse za cryptococcosis mu amphakaTikukupemphani kuti mudziwe nokha ndi vidiyo yotsatirayi yokhudza matenda ofala kwambiri pakati pa amphaka:

Nkhaniyi ndi yongofuna kudziwa zambiri, ku PeritoAnimal.com.br sitingathe kupereka chithandizo chamankhwala kapena mtundu uliwonse wa matenda. Tikukulangizani kuti mupite ndi chiweto chanu kuchipatala ngati chili ndi vuto lililonse.

Ngati mukufuna kuwerenga zina zambiri zofanana ndi Cryptococcosis mu Amphaka - Zizindikiro ndi Chithandizo, tikukulimbikitsani kuti mulowe gawo lathu la Matenda Opatsirana.