Matenda akulu amphaka amphaka - Zizindikiro, chithandizo ndi kudwala

Zamkati

• Kodi mast cell chotupa mu amphaka
• Mitundu ya zotupa zamatenda a feline mast
• Chotupa cham'mimba chotupa
• chotupa cha visceral mast cell
• Zizindikiro zamatenda am'mimbamo amphaka
• Zizindikiro za zotupa zazing'ono zamatenda amphaka
• Zizindikiro za zotupa za visceral mast cell mu amphaka
• Kuzindikira kwa chotupa cha feline mast cell
• Kuzindikira kwa chotupa cham'mimba m'matumba
• Kuzindikira kwa zotupa za visceral mast cell mu amphaka
• Chithandizo cha zilonda zam'mimba m'mphaka
• Chithandizo cha zotupa zazing'ono zamatenda amphaka
• Chithandizo cha zotupa za visceral mast cell mu amphaka

Zotupa zazing'onoting'ono zamphaka zimatha kuwonetsa mitundu iwiri yosiyana: cutaneous ndi visceral. Chotupa cha mast cell chimakhala pafupipafupi ndipo ndi mtundu wachiwiri wa khansa yoyipa ofala kwambiri mu amphaka. Zotupa zam'maso zam'mimba zimachitika makamaka mumphamba, ngakhale zimatha kupezeka m'malo ena, monga m'matumbo.

Matendawa amapangidwa ndi cytology kapena biopsy pakakhala zotupa zazing'onoting'ono zam'magazi, komanso cytology, kuyesa magazi ndi kuyerekezera kulingalira kwa zotupa za visceral mast cell. Chithandizochi chimachitidwa ndi opaleshoni pazochitika zonsezi, ngakhale mumitundu ina ya zotupa zam'mimba sizimasonyezedwa, kugwiritsa ntchito chemotherapy ndi mankhwala othandizira kukonza amphaka okhala ndi zotupa zam'mimba. Pitirizani kuwerenga nkhani iyi ya PeritoAnimal kuti mudziwe zambiri za chotupa cham'mimba, zizindikiro, chithandizo ndi madokotala ananena zawo.

Kodi mast cell chotupa mu amphaka

Mastocytoma ndi imodzi mwazotupa zomwe zingakhudze amphaka omwe ali ndi kuchulukitsa mlongoti wama cell. Maselo akulu ndi maselo omwe amachokera m'mafupa kuchokera ku hematopoietic precursors ndipo amapezeka pakhungu, minofu yolumikizana, m'mimba, komanso njira yopumira.

Ali maselo oteteza Mzere woyamba wotsutsana ndi opatsirana ophatikizana ndi timadzimadzi tawo uli ndi zinthu zomwe zimayanjanitsa ndi zotupa, monga histamine, TNF-α, IL-6, proteases, ndi zina zambiri.

Pakakhala chotupa cha maselowa, zinthu zomwe zili mu granules zawo zimatulutsidwa mokokomeza, ndikupangitsa zotsatira zakomweko kapena zochitika zomwe zimatha kubweretsa zizindikilo zingapo zamankhwala kutengera komwe zimapezeka.

Mitundu ya zotupa zamatenda a feline mast

Mu amphaka, zotupa zam'mimba zimatha kudulidwa, zikakhala pakhungu; kapena visceral, ikakhala mkatikati mwa viscera.

Chotupa cham'mimba chotupa

Ndi chotupa chachiwiri chakupha pafupipafupi mu amphaka ndi wachinayi mwa zotupa zonse za nyani. Amphaka a Siamese amawoneka kuti atha kudwala zotupa zazing'onoting'ono zam'mimba. Alipo njira ziwiri zotupa zazing'ono zam'mimba molingana ndi mawonekedwe ake:

• chifuwa: imapezeka makamaka mu amphaka azaka zopitilira 9 ndipo imagawika mawonekedwe ophatikizika (omwe amapezeka pafupipafupi komanso osawopsa, mpaka 90% yamilandu) ndi mawonekedwe ofala (owopsa, olowerera komanso oyambitsa metastasis).
• Mbiriyakale: Zimapezeka pakati pa 2 ndi 10 wazaka.

chotupa cha visceral mast cell

Zotupa zamatenda izi zimapezeka ziwalo za parenchymal monga:

• Nkhumba (kawirikawiri).
• Matumbo aang'ono.
• Ma lymph node apakati.
• Maselo a Mesenteric.

Makamaka amakhudza amphaka achikulire pakati 9 ndi 13 wazaka mulungu.

Zizindikiro zamatenda am'mimbamo amphaka

kutengera mtundu wa feline mast cell chotupa, zizindikiro zimasiyana, monga tionera pansipa.

Zizindikiro za zotupa zazing'ono zamatenda amphaka

Zotupa zazing'ono zamatenda amphaka zimatha kukhala misa imodzi kapena zingapo (20% yamilandu). Amatha kupezeka pamutu, m'khosi, pachifuwa kapena miyendo, pakati pa ena.

Kuphatikiza mitsempha zomwe nthawi zambiri zimakhala:

• Kutanthauzidwa.
• 0.5-3 masentimita awiri.
• Osati mtundu kapena pinki.

Ena zizindikiro zachipatala Zomwe zitha kuwoneka m'malo otupa ndi:

• Erythema.
• Zilonda zam'mimba.
• Kuyabwa kwakanthawi.
• Kudzivulaza.
• Kutupa.
• Edema Subcutaneous.
• Anaphylactic anachita.

Zolemba zakale za histiocytic mast kawirikawiri amatha zokha.

Zizindikiro za zotupa za visceral mast cell mu amphaka

Amphaka omwe ali ndi zotupa zam'maselo a visceral amawonetsa zizindikiro za matenda amachitidwe, monga:

• Kusanza.
• Matenda okhumudwa.
• Matenda a anorexia.
• Kuchepetsa thupi.
• Kutsekula m'mimba.
• Hyporexia.
• Kupuma kovuta ngati pali kupindika kwamphamvu.
• Splenomegaly (kukulitsa ndulu).
• Ascites.
• Hepatomegaly (chiwindi chokulitsa).
• Kuchepa kwa magazi (14-70%).
• Mastocytosis (31-100%).

Paka paka kusintha kwa ndulu, monga kukulitsa, tinthu tating'onoting'ono, kapena kutenga nawo mbali m'thupi, chinthu choyamba kuganizira ndi chotupa cham'mimba.

Kuzindikira kwa chotupa cha feline mast cell

Matendawa amatengera mtundu wa chotupa cham'mimba chomwe veterinarian amakayikira kuti feline angavutike nacho.

Kuzindikira kwa chotupa cham'mimba m'matumba

Zotupa zazing'onoting'ono zamatenda amphaka zimakayikiridwa mukamatuluka nodule wokhala ndi zomwe tafotokozazi, kutsimikiziridwa ndi a cytology kapena biopsy.

Histicitic mast cell chotupa ndi chovuta kwambiri kuchizindikira ndi cytology chifukwa cha mawonekedwe ake am'manja, maginito osadziwika komanso kupezeka kwa ma lymphoid cell.

Tiyenera kukumbukiranso kuti, mu feline eosinophilic granuloma, ma cell cell amathanso kuwonekera, omwe atha kubweretsa Matenda olakwika.

Kuzindikira kwa zotupa za visceral mast cell mu amphaka

O masiyanidwe matenda Matenda a feline visceral mast cell, makamaka a ndulu, amaphatikizapo njira izi:

• Splenite.
• Ndulu Yowonjezera.
• Hemangiosarcoma.
• Matenda a hyperplasia.
• Lymphoma.
• Matenda a Myeloproliferative.

Kuwerengera kwa magazi, biochemistry ndi kuyerekezera kulingalira ndikofunikira kuti mupeze zotupa za visceral mast cell:

• Kuyezetsa magazi: poyesa magazi, mastocytosis ndi kuchepa kwa magazi kumatha kukayikiridwa. Makamaka kupezeka kwa mastocytosis, komwe ndi kachitidwe aka mu amphaka.
• M'mimba ultrasound: ultrasound imatha kuzindikira splenomegaly kapena m'mimba ndikuyang'ana ma metastases mu mesenteric lymph node kapena ziwalo zina monga chiwindi. Ikuthandizani kuti muwone kusintha kwa ndulu parenchyma kapena ma nodule.
• x-ray pachifuwa: CXR imatilola kuti tiwone momwe mapapu alili, kufunafuna ma metastases, kupindika kwamphamvu kapena kusintha kwa cranial mediastinum.
• Zolemba: Zabwino-singano aspiration cytology mu ndulu kapena m'matumbo imatha kusiyanitsa chotupa cham'mimba kuchokera kuzinthu zina zomwe zafotokozedwazo. Ngati amachitidwa m'madzi am'mimba kapena m'minyewa yaminyewa, ma cell ndi ma eosinophil amatha kuwoneka.

Chithandizo cha zilonda zam'mimba m'mphaka

Chithandizo chotsatirachi chikuwonetsanso kusiyanasiyana kutengera mtundu wa chotupa cha mast chomwe chingachiritsidwe.

Chithandizo cha zotupa zazing'ono zamatenda amphaka

Chithandizo cha chotupa cha mast cell chimachitidwa ndi kuchotsa opaleshoni, ngakhale mutakhala mitundu yama histiocytic, yomwe imatha kubwerera pang'onopang'ono.

Kuchita opereshoni kumachiritsa ndipo kuyenera kuchitidwa ndi resection yakomweko, ngati ma cell akulu, komanso m'mizere yolimbirana nthawi zovuta. Mwambiri, kuchotsedwa kwanuko wokhala ndi masamba pakati pa 0,5 ndi 1 masentimita amalandiridwa pachotupa chilichonse cham'mimba chomwe chimapezeka ndi cytology kapena biopsy.

Zomwe zimachitika m'matumba am'mimba ndizosowa kwambiri, ngakhale zitachotsedwa mosakwanira.

Chithandizo cha zotupa za visceral mast cell mu amphaka

THE kuchotsa opaleshoni a visceral mast cell chotupa chimachitidwa mu amphaka omwe ali ndi matumbo kapena ndulu yopanda metastases kwina. Asanachotsedwe, kugwiritsa ntchito antihistamines monga cimetidine kapena chlorpheramine tikulimbikitsidwa kuti muchepetse kuwonongeka kwa mlongoti, komwe kumatha kubweretsa mavuto monga zilonda zam'mimba, kutseketsa zofooka ndi hypotension.

Nthawi yopulumuka pambuyo pa splenectomy ili pakati Miyezi 12 ndi 19, koma zoyipa zamankhwalawa zimaphatikizapo amphaka omwe ali ndi anorexia, kuonda kwambiri, kuchepa magazi, mastocythemia, ndi metastasis.

Pambuyo pa opaleshoni, nthawi zambiri amaperekedwa kwa chemotherapy wowonjezera ndi prednisolone, vinblastine kapena lomustine.

Pakakhala metastasis kapena kutengapo gawo, prednisolone pakamwa itha kugwiritsidwa ntchito pa Mlingo wa 4-8 mg / kg pa maola 24-48 aliwonse. Ngati pakufunika wowonjezera wa chemotherapeutic, chlorambucil itha kugwiritsidwa ntchito pakamwa pamlingo wa 20 mg / m2 milungu iwiri iliyonse.

Pofuna kukonza zizindikilo za amphaka ena, mankhwala a antihistamine kuchepetsa owonjezera chapamimba acidity, nseru ndi chiopsezo cha zilonda za m'mimba, antiemetics, chilimbikitso chofuna kudya kapena zotonthoza.

Tsopano popeza mukudziwa zonse za zotupa za feline mast cell, tikupangira vidiyo yotsatirayi yokhudza matenda ofala kwambiri amphaka:

Nkhaniyi ndi yongofuna kudziwa zambiri, ku PeritoAnimal.com.br sitingathe kupereka chithandizo chamankhwala kapena mtundu uliwonse wa matenda. Tikukulangizani kuti mupite ndi chiweto chanu kuchipatala ngati chili ndi vuto lililonse.

Ngati mukufuna kuwerenga zina zambiri zofanana ndi Matenda akulu amphaka amphaka - Zizindikiro, chithandizo ndi kudwala, tikukulimbikitsani kuti mulowetse gawo lina la zovuta zina.