Zamkati
- Kodi Cushing Syndrome ndi chiyani?
- Cushing syndrome mu agalu: zoyambitsa
- Zizindikiro za Cushing syndrome
- Cushing syndrome: kutengera agalu ena
- Cushing syndrome: chiyambi cha pituitary:
- Cushing syndrome: chiyambi cha adrenal glands:
- Cushing syndrome: chiyambi cha iatrogenic chifukwa chotsutsana kapena kuperekera kwa glucocorticoids ndi mankhwala ena:
- Cushing syndrome: kuzindikira ndi chithandizo
Agalu agawana nawo miyoyo yawo kwazaka zambiri. Mochulukirachulukira timakhala ndi abwenzi abweya m'nyumba zathu, kapena kupitilira amodzi, omwe tikufuna kugawana nawo chilichonse. Komabe, tiyenera kukhala osasinthasintha ndikuzindikira udindo womwe umadza ndikukhudzana ndi nyama yomwe, monga chamoyo, ili ndi ufulu. Sitiyenera kumukumbatira ndikumudyetsa komanso tikwaniritse zosowa zake zakuthupi ndi zamaganizidwe, ana agalu komanso achikulire komanso okalamba.
Zachidziwikire, ngati ndinu bwenzi losangalala komanso loyang'anira galu wanu, mukudziwa kale za matenda ofala kwambiri agalu. Munkhani yatsopano ya PeritoAnimal, tidzabweretsa zambiri za Cushing's Syndrome in Agalu - Zizindikiro ndi Zomwe Zimayambitsa, kuphatikiza pakupereka zambiri zofananira. Werengani kuti mumve momwe matendawa amakhudzira anzathu aubweya komanso zomwe muyenera kuchita nawo.
Kodi Cushing Syndrome ndi chiyani?
Cushing's syndrome imadziwikanso kuti hyperadrenocorticism, ndipo ndi matenda a endocrine (hormonal), yomwe imachitika thupi limatulutsa kuchuluka kwa mahomoni otchedwa cortisol nthawi zonse. Cortisol imapangidwa m'matope a adrenal, omwe ali pafupi ndi impso.
Mulingo wokwanira wa cortisol umatithandiza kuti matupi athu azichita moyenera kupsinjika, kumathandiza kuchepetsa kulemera kwa thupi, kukhala ndi minofu ndi khungu labwino, ndi zina zambiri. Kumbali inayi, thupi likamakulira cortisol ndikuwonjezeka kwa hormone iyi, chitetezo cha m'thupi chafooka, ndipo thupi limakumana ndi matenda ndi matenda, monga matenda ashuga. Hormone iyi yochulukirapo imathanso kuwononga ziwalo zosiyanasiyana, zomwe zimachepetsa kwambiri thanzi komanso thanzi la nyama yomwe imadwala matendawa.
Komanso, zizindikiro zimasokonezeka mosavuta ndi zomwe zimayambitsidwa ndi ukalamba wabwinobwino. Ichi ndichifukwa chake ana agalu ambiri sapezeka ndi matenda a cushing, chifukwa zizindikilozi sizimadziwika ndi omwe amasamalira ana agalu okalamba. Ndikofunikira kuzindikira zizindikiritsozo mwachangu komanso kuyesa zonse zomwe zingachitike mpaka pomwe matenda a cushing amapezeka ndi kuthandizidwa posachedwa.
Cushing syndrome mu agalu: zoyambitsa
Pali mitundu yopitilira imodzi yoyambira kapena yoyambitsa matenda agalu. Makamaka, pali atatu zoyambitsa zomwe zingayambitse kuchulukitsa kwa cortisol:
- Kulephera kwa pituitary kapena pituitary gland;
- Kulephera kwa adrenal kapena adrenal glands;
- Chiyambi cha Iatrogenic, chomwe chimachitika chachiwiri chifukwa chothandizidwa ndi glucocorticoids, corticosteroids ndi mankhwala okhala ndi progesterone ndi zotumphukira, kuchiza matenda ena agalu.
Monga tanena kale, ma adrenal gland amatulutsa timadzi ta cortisol, chifukwa chake vuto m'matendawa limatha kuyambitsa matenda obisalira. Komabe, ma adrenal gland nawonso amalamulidwa ndi mahomoni omwe amatulutsa ndi pituitary kapena pituitary gland, yomwe ili muubongo. Chifukwa chake, vuto la pituitary lingayambitsenso milingo ya cortisol kutha. Pomaliza, pali ma glucocorticoids ndi mankhwala ena omwe amagwiritsidwa ntchito pochiza matenda ena agalu, koma akagwiritsidwa ntchito molakwika, mwachitsanzo m'malo otsutsana kapena okwera kwambiri komanso nthawi yayitali, amatha kutulutsa matenda a cushing, chifukwa amasintha kapangidwe ka cortisol.
Titha kunena kuti gwero lofala kwambiri la cushing syndrome, kapena hyperadrenocorticism, pakati 80-85% ya milandu nthawi zambiri imakhala chotupa kapena hypertrophy mu pituitary, yomwe imatulutsa kuchuluka kwa mahomoni a ACTH, omwe amachititsa kuti adrenal apange cortisol yambiri kuposa yachibadwa. Njira ina yocheperako, pakati 15-20% ya milandu imapezeka m'matenda a adrenal, nthawi zambiri chifukwa chotupa kapena hyperplasia. Chiyambi cha Iatrogenic chimakhala chochepa kwambiri pafupipafupi.
Ndikofunikira kwambiri kuti chifukwa cha matenda obisalamo agalu chizindikiridwe posachedwa. Zachidziwikire, katswiri wazachipatala ayenera kuchita izi poyesa mayeso angapo ndikupereka chithandizo choyenera kwambiri chomwe chingadalire chifukwa choyambitsa matenda agalu.
Zizindikiro za Cushing syndrome
Zizindikiro zambiri zomwe zimawoneka zimatha kusokonezedwa ndi agalu. ndipo chifukwa cha izi, anthu ambiri sazindikira kuti zizindikilo zomwe mnzake wokhulupirika amapereka chifukwa chazovuta pakupanga kwa cortisol, kapena matenda a Cushing. Matendawa akamayamba pang'onopang'ono, zizindikiro zimawoneka pang'onopang'ono, ndipo zimatha kutenga miyezi kapenanso zaka kuti ziwonekere. Kumbukirani kuti si agalu onse omwe amayankha chimodzimodzi kukulitsa cortisol, chifukwa chake ndizotheka kuti si agalu onse omwe amawonetsa zisonyezo zomwezo.
Ngakhale alipo ena, the zizindikiro mZizindikiro zodziwika bwino za cushing syndrome ndi awa:
- Kuchuluka kwa ludzu ndi kukodza
- Kuchuluka chilakolako
- Mavuto akhungu ndi matenda
- Alopecia
- Hyperpigmentation pakhungu
- tsitsi labwino
- Pafupipafupi mpweya;
- kufooka kwa minofu ndi kuperewera
- Kukonda
- Kunenepa kwambiri komwe kumapezeka m'mimba (m'mimba yotupa)
- Kuchuluka kukula kwa chiwindi
- matenda obwereza a khungu
- Munthawi zamatenda, matenda amitsempha amachitika
- Zosintha pakuberekana kwazimayi
- Testrophy atrophy mwa amuna
Nthawi zina, njira yowonekera kwambiri yodziwira kuti cushing syndrome sizizindikiro, koma veterinarian akazindikira matenda achiwiri opangidwa ndi matendawa, monga matenda a shuga, sekondale hypothyroidism, kusintha kwamanjenje ndi machitidwe, mwa zina zotheka.
Cushing syndrome: kutengera agalu ena
Kuzoloŵera kwa magwiridwe antchito a adrenal glands omwe amachititsa kuchuluka kwa cortisol kumachitika pafupipafupi agalu akulu kuposa achichepere, nthawi zambiri zimachitika kuyambira zaka 6 makamaka ana agalu opitilira zaka 10. Zitha kukhudzanso agalu omwe amakumana ndi zovuta zamtundu wina wamavuto kapena zina. Zikuwoneka kuti pali umboni woganiza kuti milandu ya Cushing's syndrome yomwe imachokera kuchipatala imapezeka agalu osakwana 20 kg, pomwe milandu ya adrenal imakonda kupezeka agalu olemera makilogalamu oposa 20, ngakhale mtundu wa adrenal umapezekanso ana agalu ang'onoang'ono.
Ngakhale kugonana kwa galu sikungakhudze mawonekedwe am'madzi amtunduwu, mtunduwo ukuwoneka kuti uli ndi mphamvu. Izi ndi Mitundu ina yomwe imatha kudwala matenda a cushing syndrome, malinga ndi komwe gwero lavutoli:
Cushing syndrome: chiyambi cha pituitary:
- Daschshund;
- Kudya;
- Boston terriers;
- Kakang'ono Schnauzer;
- Chimalta Bichon;
- Bobtail.
Cushing syndrome: chiyambi cha adrenal glands:
- Mzere wa Yorkshire;
- Dachshund;
- Kakang'ono Poodle;
- M'busa waku Germany.
Cushing syndrome: chiyambi cha iatrogenic chifukwa chotsutsana kapena kuperekera kwa glucocorticoids ndi mankhwala ena:
- Wolemba nkhonya;
- M'busa wa Pyrenees;
- Kubwezeretsa kwa Labrador;
- Kudya.
Cushing syndrome: kuzindikira ndi chithandizo
Ndikofunika kwambiri kuti ngati tazindikira zina mwazizindikiro zomwe zafotokozedwa m'gawo lapitalo, ngakhale zingawoneke ngati ukalamba, tipite ku veterinator wodalirika kuti achite mayeso aliwonse omwe awona kuti ndi ofunikira Kutulutsa kapena kuzindikira matenda a cushing muubweya wathu ndikuwonetsa yankho labwino ndi chithandizo.
Wachipatala ayenera tengani mayeso angapo, monga kuyezetsa magazi, kuyesa mkodzo, ma biopsies apakhungu m'malo omwe amawonetsa kusintha, ma X-ray, ma ultrasound, mayeso ena kuti athe kuyeza kuchuluka kwa cortisol m'magazi ndipo, ngati mukukayikira komwe amachokera kuchipatala, muyeneranso kuchita CT ndi MRI.
Dokotala wa zinyama ayenera kupereka mankhwala chithandizo choyenera kwambiri cha matenda a cushing, omwe angadalire kwathunthuchiyambi kuti matendawa adzakhala nawo galu aliyense. Chithandizo chitha kukhala chamankhwala kwa moyo wonse kapena mpaka galuyo atachitidwa opaleshoni kuti awongolere milingo ya cortisol. Chithandizo chitha kukhalanso opareshoni mwachindunji kuti achotse chotupacho kapena kuthana ndi vuto lomwe limapezeka m'matope, kaya mu adrenal kapena pituitary. Chithandizo chochokera ku chemotherapy kapena radiation radiation chingatithandizenso ngati zotupa sizigwira ntchito. Kumbali inayi, ngati chifukwa cha matendawa amachokera ku iatrogenic, ndikwanira kuyimitsa mankhwala a chithandizo china chomwe akupatsidwa chomwe chikuyambitsa matendawa.
Ndikofunikira kulingalira magawo ena ambiri azaumoyo wa galu komanso zomwe angathe kuchita posankha ngati ndi bwino kutsatira chithandizo chimodzi kapena china. Komanso, tidzayenera pitani pafupipafupi kwa azachipatala kuti muwongolere milingo ya cortisol ndikusintha mankhwala ngati kuli kofunikira, komanso kuwongolera njira yogwirira ntchito.
Nkhaniyi ndi yongofuna kudziwa zambiri, ku PeritoAnimal.com.br sitingathe kupereka chithandizo chamankhwala kapena mtundu uliwonse wa matenda. Tikukulangizani kuti mupite ndi chiweto chanu kuchipatala ngati chili ndi vuto lililonse.